Investigator - Imaging, Mass Cytometry (Biotech)
We are looking for a highly motivated, agile and experienced scientist to join the Clinical Immunohistochemistry (IHC) team in the Cellular Biomarkers group within the Bioanalysis, Immunogenicity and Biomarkers (BIB) department based in Collegeville, PA. This group is responsible for developing and validating biomarker assays and its translation into the clinic in alignment with therapy area partners. Data from this group is a key component to the understanding of disease signatures and treatment responses for individual patients; and serves to enable studies to prove target engagement for novel mechanism of action and safety endpoints. Important deliverables from this group include characterization of biomarker expression, immunophenotyping and evidence of target engagement in tissue biopsies from clinical trials.
This individual will serve as a US technical expert in Imaging Mass Cytometry, providing scientific leadership and guidance on the use of Imaging Mass Cytometry with a focus on understanding the distribution of multiplexed biomarkers in the tissue microenvironment. This role will conduct and oversee all aspects of method development, trouble-shooting, validation and sample analysis for non-clinical and clinical studies requiring Imaging Mass Cytometry endpoints. The successful individual will complete all aspects of the determination; including reagent selection/optimization, sample preparation, sample acquisition, data analysis & interpretation, and presentation. Ensure all work is conducted in compliance of GCP regulations (when necessary) and following the appropriate SOPs.
We are looking for professionals with these required skills to achieve our goals:
If you have the following characteristics, it would be a plus:
Our values and expectations are at the heart of everything we do and form an important part of our culture.
These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:
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